Northrup Rand Knox (born December 24, 1928 in Buffalo, New York – died July 23, 1998 East Aurora, New York), was a Buffalo banker, sportsman, and community leader who, along with his brother Seymour, brought the National Hockey League franchise the Buffalo Sabres to Buffalo, New York. Knox is the third generation of the Knox family to serve as chairman of Marine Midland Bank and its predecessors. His father Seymour H. Knox II and grandfather Seymour H. Knox I also served as chairmen. He was also a past chairman of the Buffalo Sabres.
With his brother Seymour H. Knox III, he presented an application October 19, 1965 to obtain a National Hockey League expansion team in 1967, but was rebuffed. In 1968, the NHL Board of Governors rejected their agreement to move the Oakland Seals to Buffalo pending league approval. Finally, on December 2, 1969 the league announced its decision to expand to Buffalo and Vancouver for the 1970-71 season. Knox was a principal owner of the Buffalo Sabres from their foundation as a National Hockey League franchise in 1970 until a few months before his death.