Drew Palmisano (born July 2, 1988 in Ann Arbor, Michigan) is an American goaltender playing for the Michigan State Spartans of the NCAA.

He played junior hockey for the Omaha Lancers and the Ohio Junior Blue Jackets of the United States Hockey League in 2006-07 when he was the league's leading goaltender.

Palmisano was not drafted by any NHL team.

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